CircleDNA is powered by the most advanced Next Generation Sequencing (NGS) technology, for accurate results you can trust.

Next Generation Sequencing Technology

Your DNA, your (full) health story

Imagine that every gene is like a book. Traditional genotyping technology analyzes your genes by looking at the equivalent of only a few sentences, knowing what you are looking for – however, you remain unaware of the unknown narrative. With targeted Next Generation Sequencing (NGS) technology, we are capable of generating reports that summarize a more comprehensive volume of your health – not just a few sentences.


Why read just a sentence when you can read the whole book?


Traditional Genotyping Technology

As an example, recreational tests only look at a few variants of the BRCA 1/2 gene, which creates a high likelihood of producing a false-positive result.

Next Generation Sequencing Technology

Meanwhile, CircleDNA looks at the whole “book” for the BRCA 1/2 gene, covering 5,791 known variants that affect your risk of breast and ovarian cancer.

Number of genetic data points

Hundreds of thousands

> 3 million

Sampling data volume

Dozens of MB

> 100 MB


Microarray scanner

Novaseq (Next Generation Sequencing)

Ability to detect new mutations?



Powered by the world’s most advanced DNA technology


CircleDNA's NGS technology conducts a targeted gene sequencing, providing you with comprehensive and accurate results

Our laboratory

All samples submitted to CircleDNA are processed in our own internationally accredited laboratory with NGS technology.

We utilise NovaSeqTM 6000 systems, manufactured in the USA, by Illumina — the global market leader in DNA sequencing equipment.

Analytical Accuracy


Highest International Laboratory Quality Standards

International Accreditation


Developed by global leaders in DNA sequencing

Prof. Michael M Yang, PhD

Prof. Michael M Yang, PhD

VP (Research and Technology), Prenetics Yeung Kin-Man Chair Professor of Biomedical Sciences, City University of Hong Kong

Prof. Stephen Tsui, PhD

Prof. Stephen Tsui, PhD

Head of Division of Genomics and Bioinformatics, The Chinese University of Hong Kong

Dr. Lawrence Tzang, PhD

Dr. Lawrence Tzang, PhD

Chief Scientific Officer & Co-founder, Prenetics Founding Member, Hong Kong Society for Behavioural and Neural Genetics

Dr. Senthil Sundaram, MD

Dr. Senthil Sundaram, MD

Chief Clinical Officer, Prenetics Genetic Researcher, National Institute of Health

Our global awards