EXCLUSIVE OFFER
Win a Special Edition Health DNA Test | Breast Cancer Awareness Month 【國際乳癌關注月限定】有機會免費獲得健康風險基因測試 【国际乳癌关注月】 赢取限量版健康风险基因测试 抽選で限定パッケージHealth遺伝子検査が当たる|ピンクリボン月間 스페셜 에디션 Health 유전자 검사 증정 혜택 | 핑크 리본 캠페인
Win a Special Edition Health DNA Test | Breast Cancer Awareness Month 【國際乳癌關注月限定】有機會免費獲得健康風險基因測試 【国际乳癌关注月】 赢取限量版健康风险基因测试 抽選で限定パッケージHealth遺伝子検査が当たる|ピンクリボン月間 스페셜 에디션 Health 유전자 검사 증정 혜택 | 핑크 리본 캠페인
[Breast Cancer Awareness Month Sale] 40% Off Premium
Use code: BCAM

Our Science

CircleDNA is powered by the most advanced Whole Exome Sequencing (WES) technology, for accurate results you can trust.
laboratory equipment
Whole Exome Sequencing Technology

Your DNA, your (full) health story

Whole Exome Sequencing (WES) is the latest in DNA analytic technology used by top medical groups and leading research centres, such as the UK’s NHS, Harvard University, and Stanford University. It’s a state-of-the-art tool that allows rapid sequencing of large amounts of DNA information.

Imagine that every gene is like a book. Traditional genotyping technology analyses your genes by looking at the equivalent of just a few sentences – but without reading the entire book, you won’t know the full story of what’s happening. With Whole Exome Sequencing (WES) technology, we’re able to produce reports that summarize the whole book of your health – not just a few sentences.

Scientists working in laboratory
Why read just a sentence when you can read the whole book?
Number of genetic data points
Sampling data volume
Device
Ability to detect new mutations?
Traditional Genotyping Technology
As an example, recreational tests only look at a few variants of the BRCA 1/2 gene, which creates a high likelihood of producing a false-positive result.
Hundreds of thousands
Dozens of MB
Microarray scanner
No
Whole Exome Sequencing Technology
Meanwhile, CircleDNA looks at the whole “book” for the BRCA 1/2 gene, covering 5,791 known variants that affect your risk of breast and ovarian cancer.
> 31 million
Several GB
Novaseq (next generation sequencing)
Yes
Why read just a sentence...
Traditional Genotyping Technology
(Example) Recreational tests only look at a few variants of the BRCA 1/2 gene, which creates a high likelihood of producing a false-positive result.
...when you can read the whole book?
Whole Exome Sequencing Technology
Meanwhile, CircleDNA looks at the whole “book” for the BRCA 1/2 gene, covering 5,791 known variants that affect your risk of breast and ovarian cancer.
Hundreds of Thousands
Number of Genetic Data Points
> 31 Million
Dozens of MB
Sampling Data Volume
Several GB
Microarray Scanner
Device
Novaseq (Next Generation Sequencing)
No
Ability to Detect New Mutations?

Powered by the world’s most advanced DNA technology

Whole Exome Sequencing
CircleDNA’s WES technology conducts a full scan on all your protein-coding genes, providing you with comprehensive and accurate results.
23andMe
Circle Exome
700K data points
50x more than 23andMe
31M data points

Our laboratory

All samples submitted to CircleDNA are processed in our own internationally accredited laboratory with WES technology.

We utilise NovaSeqTM 6000 systems, manufactured in the USA, by Illumina — the global market leader in DNA sequencing equipment.

Analytical Accuracy
99.9%
Highest International Laboratory Quality Standards
International Accreditation
Scientists working in laboratory

Backed by Cutting-Edge Science

Prenetics leadership headshot
Prof. Michael M Yang, PhD
VP (Research and Technology), Prenetics Yeung Kin-Man Chair Professor of Biomedical Sciences, City University of Hong Kong
Prenetics leadership headshot
Prof. Stephen Tsui,
PhD
Head of Division of Genomics and Bioinformatics, The Chinese University of Hong Kong
Prenetics leadership headshot
Dr. Lawrence Tzang,
PhD
Chief Scientific Officer & Co-founder, PreneticsFounding Member, Hong Kong Society for Behavioural and Neural Genetics
Prenetics leadership headshot
Dr. Senthil Sundaram,
MD
Chief Clinical Officer, Prenetics Genetic Researcher, National Institute of Health

Our global awards